Fahr Beyond

Supporting research into Fahr's Disease

Diagnosing Fahr's 

Fahr Beyond is privileged to have as it's lead on medical input a world leading professor of neurology (specialising in Parkinsonism conditions), and is based at the National Hospital for Neurology and Neurosurgery in London, UK. Furthermore, we have communication with other leading Neurologist and Neurosurgeons in four different National Health Service Trusts across the UK. 


Not only that we stay up to date with the current medical and academic literature on Fahr's and Fahr's like conditions. 


Fahr's usually is only evident on a Computerised Tomography scan, it has been noted that Magnetic Resonance Imaging scans can miss the disease. Fahr's has quite a unique CT trace, showing areas of calcification in the Basal Ganglia and the Frontal Cortex; however it has been known to impact  


Fahr's Disease

Fahr's is a complex series of conditions with on the one hand Fahr's Disease which is usually viewed as a single aetiology that is attributable to genetic mutations and is predominantly inherited through the family line. 


If this is the case there is need to gain a full understanding of the family line, and any incidents of Fahr's or more commonly what was seemingly Parkinson's or Alzheimer's in parents/older siblings/other higher tier relatives such as Uncles/Aunts/Grandparents/Siblings of Grandparents. 


Fahr's Disease needs to be carefully verified, as this can have large ramifications upon the patient being diagnosed; due to the premise of the disease being genetic it is of a high likelihood that this would be passed onto any children they have or intend to have in the future. 



Fahr's Syndrome 

Fahr's Syndrome usually refers to the condition when there are multiple aetiologies of the calcification.  This is where there are usually external environmental factors that have led to the calcification of the basal ganglia. Some examples include: significant trauma to the head, where fontanelles fail to close in infancy leading to other brain complications, toxicological exposure, mutation from significant immunodisease, brain infection, and other environmental factors. 


In this case it is likely that there will not be any family history of Fahr's, Parkinson's or Alzhiemer's, and if there is care should be taken to establish whether these are incidental or there is a traceable commonality. 


(It should be noted that other conditions such as a mutation of the PARAT hormone could present itself as similar to Fahr's).



Symptoms

Symptoms of Fahr's are outline on the home page. 


Patients may present as asymptomatic and will not develop any symptoms and live a healthy full life. In this case ongoing monitoring could be a wise precaution. 


On the other hand symptoms normally manifest themselves throughout the 30-60 age range with the most common being 40-50 years old; however it should be noted there are recorded cases of patients in their 20s and 70s. 


Symptoms can take the form as neurological impairment, in other as physiological impairment and sometimes as both. 


Some literature refers to timelines of deterioration and in extreme cases mortality. We believe it is up to your professional judgement to establish appropriate care. 


It is essential to note that there is no correlation between the extent of calcification and the rate of neurological impairment.


Diagnosing 

It is really important to be open with patients about Fahr's and the next steps to support, we have found many Fahr's patients have a lack of knowing where to go for support particularly as the condition is seemingly rare. 


We are here to support patients within the scope of our limit resources as a charity and to signpost to other supporting organisations. 


It is important to be open with patients that there is no known cure for Fahr's Disease, and that whilst some countries have experimented with medication for other conditions there is no definitive evidence to support that they work.